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ChemicalBook--->CAS DataBase List--->108153-74-8

108153-74-8

108153-74-8 Structure

108153-74-8 Structure
IdentificationBack Directory
[Name]

Secretin (human)
[CAS]

108153-74-8
[Synonyms]

Rg 1068
SECRETINHCL
SECRETIN, HUMAN
Unii-A0426J905j
Secretin (28-54), human
Secretin (human) USP/EP/BP
Secretin human, ≥97% (HPLC)
HSDGTFTSELSRLREGARLQRLLQGLV-NH3
HSDGTFTSELSRLREGARLQRLLQGLV-NH2
Secretin (pig), 15-L-glutamic acid-16-glycine-
Secretin (swine), 15-L-glutamic acid-16-glycine-
HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-GLU-GLY-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH2
H-HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-GLU-GLY-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH2
H-HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-GLU-GLY-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH3
HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-GLU-GLY-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH2 HUMAN
H-His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Arg-Glu-Gly-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH2 hydrochloride salt
L-His-L-Ser-L-Asp-Gly-L-Thr-L-Phe-L-Thr-L-Ser-L-Glu-L-Leu-L-Ser-L-Arg-L-Leu-L-Arg-L-Glu-Gly-L-Ala-L-Arg-L-Leu-L-Gln-L-Arg-L-Leu-L-Leu-L-Gln-Gly-L-Leu-L-Val-NH2
L-Valinamide, L-histidyl-L-seryl-L-.alpha.-aspartylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-.alpha.-glutamyl-L-leucyl-L-seryl-L-arginyl-L-leucyl-L-arginyl-L-.alpha.-glutamylglycyl-L-alanyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminylglycyl-L-leucyl-
[EINECS(EC#)]

241-105-3
[Molecular Formula]

C130H220N44O40
[MDL Number]

MFCD00135670
[MOL File]

108153-74-8.mol
[Molecular Weight]

3039.41
Chemical PropertiesBack Directory
[density ]

1.49±0.1 g/cm3(Predicted)
[storage temp. ]

−20°C
[form ]

powder
[Water Solubility ]

Soluble to 1 mg/ml in water
Safety DataBack Directory
[WGK Germany ]

3
[RTECS ]

VS4030000
Hazard InformationBack Directory
[Uses]

Stimulates pancreatic and gastric secretions to aid in the diagnosis of pancreatic exocrine dysfunction and the diagnosis of gastrinoma.
[Brand name]

SecretinKabi (KabiVitrum, Sweden).
[General Description]

Secretin is a gastrointestinal hormone and a neuropeptide. It is synthesized from a precursor protein and shares sequence homology with other secretin family proteins like glucagon and vasoactive intestinal peptide (VIP).
[Biochem/physiol Actions]

Secretin regulates the secretion of gastric acid and pancreatic bicarbonates. It serves as an antidiuretic hormone in the neurohypophysial-renal axis and participates in osmoregulation. Secretin mediates its function through the G-protein coupled secretin receptors. It regulates the pH of the duodenal by modulating gastric acid secretion.
[storage]

Store at -20°C
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