| Identification | Back Directory | [Name]
Anwuligan | [CAS]
107534-93-0 | [Synonyms]
Calophyn
Anwuligan
Macelignan
ANWULIGNAN
(+)-Anwulignan
Macelignan, >98%
Anwuligan（Macelignan）
Macelignan >=98% (HPLC)
Anwuligan, 98%, from Schisandra chinensis
4-(2S,3R)-4-(1,3-benzodioxol-5-yl-2-3-dimetybty]-2_methoxyphenol
4-[(2S,3R)-4-(1,3-Benzodioxol-5-yl)-2,3-dimethylbutyl]-2-methoxyphenol
Phenol,4-[(2S,3R)-4-(1,3-benzodioxol-5-yl)-2,3-diMethylbutyl]-2-Methoxy- | [Molecular Formula]
C20H24O4 | [MDL Number]
MFCD09953803 | [MOL File]
107534-93-0.mol | [Molecular Weight]
328.4 |
| Chemical Properties | Back Directory | [Melting point ]
70-71℃ | [Boiling point ]
467.0±40.0 °C(Predicted) | [density ]
1.159 | [Fp ]
236℃ | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : ≥ 30 mg/mL (91.35 mM) | [form ]
powder | [pka]
10.19±0.20(Predicted) | [color ]
White | [LogP]
5.220 (est) |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the root or bark of Schisandra chinensis. | [Uses]
Anwuligan has anti-tumor and coagulation effects. | [Definition]
ChEBI: 4-[(2S,3R)-4-(1,3-benzodioxol-5-yl)-2,3-dimethylbutyl]-2-methoxyphenol is a lignan. | [Biological Activity]
Macelignan is a neuroprotective lingan isolated from nutmeg (Myristica fragrans) th at protects dopaminergic neurons from inflammatory degeneration. Apparentlythe neuroprotective effect of macelignan is mediated by PPARγ activation and arginase-1 expression. Macelignan inhibits LPS induced production of NO as well and inflammatory cytokines including TNF and IL- 1β in primary cultures of microglia. | [target]
PAFR | Antifection | [storage]
Store at -20°C |
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