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ChemicalBook--->CAS DataBase List--->105618-26-6

105618-26-6

105618-26-6 Structure

105618-26-6 Structure
IdentificationBack Directory
[Name]

NOR-BINALTORPHIMINE DIHYDROCHLORIDE
[CAS]

105618-26-6
[Synonyms]

NORBNI
NOR-BNL 2HCL
norbinaltorphimine
NOR-BNI DIHYDROCHLORIDE
Nor-binaltorphimine2HCl
N-DeMethylbinaltrorphiMine
N-DESMETHYLBINALTORPHIMINE
NOR-BINALTORPHIMINE DIHYDROCHLORIDE
4,8:11,15-Dimethano-20H-bisbenzofuro[2,3-a:3'',2''-i]
17,17'-(Dicyclopropylmethyl)-6,6',7,7'-6,6'-imino-7,7'-binorphinan-3,4',14,14'-tetroldihydrochloride
17,17'-(DICYCLOPROPYLMETHYL)-6,6',7,7'-6,6'-IMINO-7,7'-BINORPHINAN-3,4',14,14'-TETROL DIHYDROCHLORIDE
4,8:11,15-Dimethano-20H-bisbenzofuro[2,3-a:3',2'-i] dipyrido[4,3-b:3',4'-h]carbazole-1,8a,10a,18-tetrol, 7,12-bis(cyclopropyl methyl)-5,6,7,8,9,10,11,12,13,14,19a,20b-dodecahydro-, (4bS,8R,8aS,10aS,11R,14aS,19aR,20bR)
4,8:11,15-DIMETHANO-20H-BISBENZOFURO[2,3-A:3',2'-I]DIPYRIDO[4,3-B:3',4'-H]CARBAZOLE-1,8A,10A,18-TETROL, 7,12-BIS(CYCLOPROPYLMETHYL)-5,6,7,8,9,10,11,12,13,14,19A,20B-DODECAHYDRO-, (4BS,8R,8AS,10AS,11R,14AS,19AR,20BR), DIHYDROCHLORIDE
4,8:11,15-Dimethano-20H-bisbenzofuro(2,3-A:3',2'-I)dipyrido(4,3-B:3',4'-H)carbazole-1,8A,10A,18-tetrol, 7,12-bis(cyclopropylmethyl)-5,6,7,8,9,10,11,12,13,14,19A,20B-dodecahydro-20-methyl-, (8R-(4br*,8alpha,8abeta,10aalpha,11beta,14ar*,19aalpha,20bbeta))-
[Molecular Formula]

C40H45Cl2N3O6
[MDL Number]

MFCD00069374
[MOL File]

105618-26-6.mol
[Molecular Weight]

734.71
Chemical PropertiesBack Directory
[Appearance]

Tan solid
[density ]

1.63±0.1 g/cm3(Predicted)
[storage temp. ]

−20°C
[solubility ]

artificial CSF: soluble2mg/mL (prepare with sonication for 4 minutes)
[form ]

Solid
[pka]

9.11±0.60(Predicted)
[color ]

tan
[Water Solubility ]

water: 50mM
[Stability:]

Hygroscopic
[EPA Substance Registry System]

Norbinaltorphimine (105618-26-6)
Hazard InformationBack Directory
[Chemical Properties]

Tan solid
[Biological Activity]

A selective κ -opioid receptor antagonist.
[Uses]

nor-Binaltorphimine dihydrochloride is a selective KOR antagonist.
[Definition]

ChEBI: Norbinaltorphimine is a member of isoquinolines.
[Biochem/physiol Actions]

Highly selective k-opioid receptor antagonist. nor-Binaltorphimine has antidepressant properties.
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-36
[WGK Germany ]

-
[RTECS ]

IO1320000
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