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ChemicalBook--->CAS DataBase List--->100986-86-5

100986-86-5

100986-86-5 Structure

100986-86-5 Structure
IdentificationBack Directory
[Name]

D-OFLOXACIN
[CAS]

100986-86-5
[Synonyms]

DR 3354
DS-4632
Aids002308
Aids-002308
D-OFLOXACIN
d-Levofloxacin
Levofloxacin-5
Ofloxacin R-Isomer
Levofloxacin R-IsoMer
D-Isomer of ofloxacin
(R)-Ofloxacin,98%e.e.
Levofloacin Impurity E
(R)-9-fluoro-3-methyl-
Levofloxacin Impurity L
Levofloacin USP Impurity E
Levofloxacin EP Impurity A
Levofloxacin (R)-Ofloxacin
Levofloxacin Impurity 6(R-Isomer)
Ofloxacin Impurity 2((R)-Ofloxacin)
Levofloxacin EP Impurity A(Levofloxacin R-Isomer)
Levofloxacin Hydrochloride ImpurityⅠ: (Dextrofloxacin)(R)-Levofloxacin
(R)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
R-9-fluoro-2, 3-dihydro-3-Methyl-10-(4-Methyl-1-piperazinyl)-7-oxo-7h-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
(3R)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-pyrido[1, 2,3-de][1,4]benzoxazine-6-carboxylic acid
7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (R)-
7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (3R)-
[3R,(+)]-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (3R)- (9CI)
(2R)-7-Fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
R-Ofloxacin (25 mg) ((R)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid)
Levofloxacin impurity 9/Ofloxacin R-Isomer/(R)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
[Molecular Formula]

C18H20FN3O4
[MDL Number]

MFCD00869643
[MOL File]

100986-86-5.mol
[Molecular Weight]

361.37
Chemical PropertiesBack Directory
[Melting point ]

185 °C
[Boiling point ]

571.5±50.0 °C(Predicted)
[density ]

1.48±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 10 mg/ml
[form ]

A crystalline solid
[pka]

5.19±0.40(Predicted)
[color ]

Off-white to light yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P264-P270-P301+P312-P330-P501
[HS Code ]

2934990002
Hazard InformationBack Directory
[Uses]

Fluorinated quinolone antibacterial. An enantiomer of Levofloxacin (L360000).
[Definition]

ChEBI: Dextrofloxacin is the (R)-enantiomer of ofloxacin. It has a role as an antibacterial drug, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, a topoisomerase IV inhibitor and a DNA synthesis inhibitor. It is a 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, a quinolone antibiotic and a fluoroquinolone antibiotic. It is an enantiomer of a levofloxacin.
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