Identification | Back Directory | [Name]
6-AMINO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE | [CAS]
1002726-62-6 | [Synonyms]
6-AMino-2,2-diMethyl-2H-p... 6-Amino-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3 6-Amino-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H) 6-AMINO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE 2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one, 6-aMino-2,2-diMethyl- 6-amino-2,2-dimethyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one | [Molecular Formula]
C9H11N3O2 | [MDL Number]
MFCD10000812 | [MOL File]
1002726-62-6.mol | [Molecular Weight]
193.2 |
Chemical Properties | Back Directory | [Boiling point ]
420.3±45.0 °C(Predicted) | [density ]
1.256 | [Fp ]
208 | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [form ]
solid | [pka]
10.79±0.40(Predicted) | [InChI]
InChI=1S/C9H11N3O2/c1-9(2)8(13)12-7-5(14-9)3-4-6(10)11-7/h3-4H,1-2H3,(H3,10,11,12,13) | [InChIKey]
HSYOWUOUDXDSMC-UHFFFAOYSA-N | [SMILES]
O1C(C)(C)C(=O)NC2=NC(N)=CC=C12 |
Hazard Information | Back Directory | [Uses]
6-Amino-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one is a useful intermediate for the preparation of protein kinase inhibitors. | [Application]
6-amino-2,2-dimethyl-2h-pyrido[3,2-b][1,4]oxazin-3(4h)-one is the key intermediate of Fostamatinib, which is a medication approved by the U.S. Food and Drug Administration since 2018 for the treatment of chronic immune thrombocytopenia (ITP). |
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